National Library of  Medicine
Influenza ward, Aix-les-Bains France, National Library of Medicine

The influenza pandemic of 1918 was one of the worst disease outbreaks in human history.  The best evidence indicates that this disaster began at Camp Funston, an  army base in Kansas on March 8, 1918.  An influenza virus mutated into a lethal strain. It arrived in Europe on American troop ships in early April 1918, and perhaps mutated again. The epidemic traveled fast in three waves of infection, reaching almost every corner of the world by the spring of 1919, when the virus played itself out.
Influenza killed over 20 million people in the span of a year.  This was more than twice the number of people who died in the horrific battles of World War I.