National Library of  Medicine
Smallpox, circa 1920, NLM

There were many health and environmental problems that Dr. Hayne faced during his first year on the job.

In 1912, epidemics and outbreaks of infectious disease were the major health concerns.  Disease reporting was an inaccurate process, but some statistics were presented in the annual report.
There were 392 reported cases of smallpox and two reported deaths: Dr. Hayne noted that the white population was about 75% vaccinated and the black population was about 60% vaccinated..."there is much work yet to be done before we finally succeed in stamping out smallpox."
State Board of Health. Thirty-third Annual Report of the State Board of Health of South Carolina for the Fiscal Year 1912 to the Legislature of South Carolina. Columbia, SC: Gonzales & Bryan, 1913.