Yellow Fever Epidemics
in South Carolina
•1699 First yellow fever epidemic in Charleston
•1700’s Yellow fever epidemics were recorded in Charleston in 1706, 1711, 1717, 1718, 1719, 1730-1739, 1745, 1748, 1790-99 •1800's   Yellow fever epidemics were recorded  in Charleston in 1800, 1802, 1804, 1817, 1820, 1821, 1824, 1827, 1828, 1838, 1839, 1849, 1852, 1854, 1856, 1858, 1864, 1871, and 1876.
There were recurrent episodes of yellow fever throughout the 1700’s and well into the 1870’s.  The last major outbreak in Charleston occurred in 1876.
There was little that doctors of the time could do: they did not understand the causes of the disease or know any effective treatments.

Farley, M. Foster. An Account of the History of Stranger’s Fever in Charleston, 1699-1876.  Washington, DC: University Press of America, 1978.
Waring, Joseph I. A History of Medicine in South Carolina, 1825-1900. Columbia, SC: South Carolina Medical Association, 1967.