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Bureau of Disease Control

Useful Information

SC List of Reportable Conditions (pdf)

SC Laboratory List of Reportable Conditions (pdf)

2014 South Carolina Reportable Disease Form (pdf)

Changes in the 2013 List of Reportable Conditions

A-Z List of Reportable Conditions in SC

What to Report 

How and When to Report

Regional Public Health Offices 

South Carolina List of Reportable Conditions


Disease Reporting by Healthcare Providers, Hospitals, Clinics, Other Healthcare Facilities

South Carolina Law (44-29-10) and Regulations (61-20) require reporting of specified contagious and infectious diseases and conditions to the local health department

“in the form and manner as prescribed by DHEC in regulations concerning infectious diseases.  The reports must be made to the Bureau of Disease Control in the manner required in the regulations.  When available, clinical information supporting the diagnoses, including results of specific diagnostic tests, must be included.”

In South Carolina, these diseases and conditions are specified in the List of Reportable Conditions (pdf), published annually.  The list also includes outbreaks of disease or unusual clusters of illness, events such as animal (mammal) bites and pesticide poisoning, and findings suggestive of disease (e.g., hemolytic uremic syndrome).  Diseases do not have to be confirmed to be reported -- actions to prevent further spread of disease may be necessary while confirmatory tests are pending.  (View A-Z list of Reportable Conditions.)

Reporting by Laboratories

The Laboratory List of Reportable Conditions specifies which conditions/findings must be reported to SC DHEC by clinical laboratories. 


Federal HIPAA legislation allows disclosure of protected health information, without consent of the individual, to public health authorities for the purpose of preventing or controlling disease. (HIPAA 45 CFR §164.512)


For schools subject to the Family Education Rights and Privacy Act (FERPA), FERPA allows reporting of illnesses without specific parent permission if a “health or safety emergency” exists.  SC DHEC and the SC Department of Education have jointly determined that conditions where reports are requested immediately or within 24 hours by phone, including all clusters or outbreaks of illnesses, may be reported to SC DHEC by name, without parental consent.  Disclosure of this information is documented in the student’s/students’ record(s) per local policies for FERPA compliance. 

Conditions where reporting is required within 3 days may be reported to DHEC by name with parental consent.  De-identified reporting is also allowed for these conditions.  School personnel should work with local education agency nursing leadership, or local health department epidemiology staff to review processes for de-identified reporting of illnesses that may spread in schools, especially varicella.

Changes in the 2013 List of Reportable Conditions

Providers with questions about reporting of specific list items should contact their Regional Public Health Epidemiology Office or the Division of Acute Disease Epidemiology.

  1. Many conditions now have a shortened reporting time.
    **All conditions that were reportable in 7 days are now reportable in 3 days.**
    All influenza deaths are now reportable in 24 hours, not just flu deaths of children 18 and younger.
  2. Alphabetical Order
    Reportable Conditions are now listed in alphabetical order.   
    Arboviral illnesses, are now listed as separate conditions: Eastern Equine Encephalitis, La Crosse Encephalitis, St. Louis Encephalitis, and West Nile Virus.  These are not all of the Arboviral conditions.  Providers are encouraged to report any other acute cases of arborviral fever/meningo-encephalitis as “unusual diseases.”
  3. Some conditions have been combined to assure appropriate/complete reporting:
    While most conditions are listed alphabetically, the rarely reported viral hemorrhagic fevers (Ebola, Lassa, Marburg viruses) are clustered together.  
    • All Acute Hepatitis infections (A, B & E) are reportable in 24 hours.
    • All Chronic Hepatitis Infections (B, C & D) are reportable in 3 days.
    • All HIV positive tests (detection and confirmatory results) are reportable.
    • All HIV CD4 results are reportable.
    • All lead tests are reportable, not just tests on children or elevated test results.
  4. Timing of Reporting is now indicated by Typeface and Symbols
    Reporting times are indicated by symbols.
    An exclamation point (!) and bold-face font indicate a condition Immediately Reportable by Phone
          ! Botulism
    An asterisk (*) indicates a condition Urgently Reportable within 24 hours by phone.
          * Eastern Equine Encephalitis
    All other conditions are reportable within 3 days.
          Leprosy (Hansen’s Disease)
  5. Change in reporting criteria for Rabies PEP
     “Rabies Post Exposure Prophylaxis (when recommended)” has been changed to “Rabies Post Exposure Prophylaxis (PEP) (when administered).”  Providers should report the date when the first doses of Rabies PEP (generally vaccine and immune globulin) are administered.  Dates of subsequent doses are not required.
  6. Change in reporting criteria for Varicella
    All varicella cases will be reportable to SC DHEC within 3 days of diagnosis by a healthcare provider.  This includes identification of varicella by a school nurse.
  7. New Conditions
    • Babesiosis, a tickborne infection, is reportable within 3 days of diagnosis.
    • HIV and AIDS clinical diagnosis” has been “promoted” from the footnotes and added as a separately reportable condition. 
  8. Conditions no longer Reportable
    • Enterobacteriaceae, carbapenem-resistant (CRE) (E. coli and Klebsiella pneumoniae) reporting has been removed.  These data are now reported to the National Healthcare Safety Network (NHSN). 
    • Glanders (Burkholderia mallei) has been removed.  This condition is no longer nationally reportable.
    • Melioidosis (Burkholderia pseudomallei) has been removed.  This condition is no longer nationally reportable.
    • Pesticide poisoning has been removed.  These cases should be promptly managed by Poison Control 1-800-222-1222.
    • Staphylococcus aureus, Methicillin resistant, bloodstream infections (MRSA-BSI) reporting has been removed.  These data are now reported to the NHSN.
  9. Verbiage Changes
    • HIV HLA-B5701 now reads “HLA-B5701 and co-receptor assay (L)” and is only reportable by laboratories.
    • “Meningitis, aseptic” has been changed to “Meningo-encephalitis, aseptic.”
    • “Rickettsiosis, Spotted fever (e.g., RMSF)” has been changed to “Rocky Mountain Spotted Fever (Spotted Fever group).”

Reportable Conditions in South Carolina

Report all suspected and confirmed cases, including preliminary clinical and laboratory results.

A-C               D-G               H-I               J-L                M-P               Q-S               T-Z

Disease, Condition or Event

Time for Reporting


  Any outbreak or unusual disease Immediately, by phone (1) (5)
** Any intentional biological, chemical, or radiological event Immediately, by phone  
  AIDS, clinical diagnosis Within 3 days  
  Anaplasmosis (Anaplasma phagocytophilum) Within 3 days  
  Animal (mammal) bites Urgently, within 24 hours, by phone (6)
** Anthrax (Bacillus anthracis) Immediately, by phone (5)
  Babesiosis Within 3 days  
** Botulism (Clostridium botulinum or Botulinum toxin) Immediately, by phone  
** Brucellosis Urgently, within 24 hours, by phone (5)
  Campylobacteriosis Within 3 days  
  Chancroid (Haemophilus ducreyi) Within 3 days  
  Chlamydia trachomatis, genital site Within 3 days  
** Clostridium botulinum Immediately, by phone  
  Creutzfeldt-Jakob Disease (Age < 55 years) Within 3 days  
  Cryptosporidiosis Within 3 days  
  Cyclosporiasis Within 3 days  
  Dengue (Flavivirus) Urgently, within 24 hours, by phone (5)
  Diphtheria Urgently, within 24 hours, by phone (5)
  Eastern Equine Encephalitis Urgently, within 24 hours, by phone (5)
  E. coli, shiga toxin - producing (STEC), including E. coli O157:H7 Urgently, within 24 hours, by phone (5)
  Ebola Virus (Viral Hemorrhagic Fever) Immediately, by phone  
  Ehrlichiosis (Ehrlichia species) Within 3 days  
  Giardiasis Within 3 days  
  Gonorrhea Within 3 days  
  Haemophilus influenzae, all types, invasive disease Urgently, within 24 hours, by phone (3) (5)
  Hansen's Disease (Leprosy) Within 3 days  
  Hantavirus Urgently, within 24 hours, by phone  
  Hemolytic uremic syndrome (HUS) Urgently, within 24 hours, by phone  
  Hepatitis A, B, & E acute Urgently, within 24 hours, by phone  
  Hepatitis B, C, & D chronic Within 3 days  
  Hepatitis B Surface Antigen positive with each pregnancy Within 3 days  
  HIV and AIDS, clinical diagnosis Within 3 days  
  HIV CD4 tests (all results) Within 3 days (L)
  HIV subtype, genotype, and phenotype Within 3 days (L)
  HIV positive test results (detection and confirmatory tests) Within 3 days  
  HIV viral load - all results Within 3 days (L)
  HIV HLA-B5701 and co-receptor assay Within 3 days (L)
  Influenza A, avian or other novel Immediately, by phone  
  Influenza associated deaths (all ages) Urgently, within 24 hours, by phone  
  Influenza Lab-confirmed cases (culture, RT-PCR, DFA, IFA) Within 3 days  
  Influenza Lab-confirmed Hospitalizations (aggregate report of totals) Within 3 days  
  Influenza Positive rapid flu tests (aggregate report of totals) Within 3 days  
  LaCrosse Encephalitis Urgently, within 24 hours, by phone (5)
  Lassa Fever (Viral Hemorrhagic Fever) Immediately, by phone  
  Lead tests, all results Within 3 days  
  Legionellosis (all positive tests) Within 3 days (5)
  Leprosy (Hansen's Disease) Within 3 days  
  Leptospirosis Within 3 days  
  Listeriosis Within 3 days (5)
  Lyme disease (Borrelia burgdorferi) Within 3 days  
  Lymphogranuloma venereum Within 3 days  
  Malaria (Plasmodium species) Within 3 days  
  Marburg Fever (Viral Hemorrhagic Fever) Immediately, by phone  
  Measles (Rubeola) Immediately, by phone  
  Meningo-encephalitis, aseptic Within 3 days  
  Meningococcal disease Immediately, by phone (3) (4) (5)
  Mumps Urgently, within 24 hours, by phone  
  Pertussis Urgently, within 24 hours, by phone  
** Plague (Yersinia pestis) Immediately, by phone (5)
  Poliomyelitis Immediately, by phone  
** Psittacosis (Chlamydophila psittaci) Within 3 days  
** Q fever (Coxiella burnetii) Urgently, within 24 hours, by phone  
  Rabies (human) Immediately, by phone  
  Rabies Post Exposure Prophylaxis (when administered) Within 3 days (6)
  Rocky Mountain Spotted Fever (Spotted Fever Group) Within 3 days  
  Rubella (includes congenital) Urgently, within 24 hours, by phone  
  Salmonella typhi (Typhoid fever) Urgently, within 24 hours, by phone (5)
  Salmonellosis Within 3 days (5)
  Shiga toxin - producing E. coli (STEC), including E. coli O157:H7 Urgently, within 24 hours, by phone (5)
  Shigellosis Within 3 days (5)
** Smallpox (Variola) Immediately, by phone  
  Staphylococcus aureus, Vancomycin-resistant or intermediate (VRSA/VISA) Urgently, within 24 hours, by phone (5)
  Streptococcus group A, invasive disease Within 3 days (3)
  Streptococcus group B, age < 90 days Within 3 days  
  Streptococcus pneumoniae, invasive, Within 3 days (2) (3)
  St. Louis Encephalitis Urgently, within 24 hours, by phone (5)
  Syphilis, congenital, primary or secondary (lesion or rash) Urgently, within 24 hours, by phone  
  Syphilis, latent or tertiary, or positive serologic test Within 3 days  
  Tetanus Within 3 days  
  Toxic Shock (specify staphylococcal or streptococcal) Within 3 days  
  Trichinellosis (T. spiralis) Urgently, within 24 hours, by phone  
  Tuberculosis Urgently, within 24 hours, by phone (5)
** Tularemia Urgently, within 24 hours, by phone (5)
  Typhoid fever (Salmonella typhi) Urgently, within 24 hours, by phone (5)
** Typhus, epidemic (Rickettsia prowazekii) Urgently, within 24 hours, by phone  
  Varicella Within 3 days  
  Vibrio, all types, including Vibrio cholerae O1 and O139 Urgently, within 24 hours, by phone (5)
** Viral Hemorrhagic Fever (Ebola, Lassa, Marburg Viruses) Immediately, by phone  
  VISA: Vancomycin Intermediate-resistant Staphylococcus aureus Urgently, within 24 hours, by phone (5)
  VRSA: Vancomycin-Resistant Staphylococcus aureus Urgently, within 24 hours, by phone (5)
  West Nile Virus Urgently, within 24 hours, by phone (5)
  Yellow Fever (Flavivirus) Urgently, within 24 hours, by phone  
  Yersiniosis (Yersinia, not pestis) Within 3 days  


** Potential agent of bioterrorism
(L) Only Labs required to report.
1. An outbreak is the occurrence of more cases of disease than normally expected within a specific place or group of people over a given time.  Clinical specimens may be required.
2. Reports should specify the site from which the isolate was obtained and the drug susceptibility profile. 
3. Invasive disease = isolated from normally sterile site: blood, bone, CSF, joint, pericardial, peritoneal, or pleural fluid, protected bronchial sampling or from lung aspirate/biopsy, necrotizing fasciitis, and cellulitis only if isolate is from a tissue biopsy.  Always specify site of isolate.
4.  Report Gram-negative diplococci in blood or CSF.
5. Labs are requested to submit these isolates, positive serologies, or specimens to the DHEC Bureau of Laboratories for confirmatory testing or genotyping. 
6. Rabies Post-Exposure Prophylaxis (PEP) guidance:  Consultation is available from the DHEC Regional Offices (see lists for daytime and after hours numbers).

What to Report

  • Patient’s name
  • Patient’s complete address, phone, date of birth, race, sex, county, social security number
  • Physician’s name and phone number
  • Name, institution, and phone number of person reporting
  • Disease or condition
  • Date of diagnosis
  • Symptoms
  • Date of onset of symptoms
  • Date of report
  • Lab results, specimen site, collection date
  • If female, pregnancy status
  • Status: In child care or a food-handler

How and When to Report

Submit reports by one of the following methods:

  1. Conditions Immediately Reportable or Reportable Within 24 hours:
  2. Conditions Reportable Within 3 Days:
  3. HIV, AIDS, and STDs (excluding Hepatitis):. To report these conditions call 1-800-277-0873; or submit electronically via CHESS, DHEC’s electronic reporting system (call 1-800-917-2093 to learn more about electronic disease reporting); or submit a DHEC 1129 Disease Reporting Card or appropriate CDC Case Report Form in a confidential envelope to:

    Division of Surveillance & Technical Support, Mills/Jarrett Complex
    Box 101106, Columbia, SC  29211

Regional Public Health Offices Contact Information for Disease Reporting


  • Berkeley, Charleston, Dorchester
    4050 Bridge View Drive, Suite 600
    N. Charleston, SC 29405
    Phone: (843) 953-0043
    Fax: (843) 953-0051
    Nights / Weekends:
    (843) 441-1091
  • Beaufort, Colleton, Hampton, Jasper
    219 S. Lemacks Street
    Walterboro, SC 29488
    Phone: (843) 549-1516
    Fax: (843) 549-6845
    Nights / Weekends:
    (843) 441-1091
  • Allendale, Bamberg, Calhoun, Orangeburg
    P.O. Box 1126
    1550 Carolina Avenue
    Orangeburg, SC 29116
    Phone: (803) 268-5866
    Fax: (843) 549-6845
    Nights / Weekends:
    (843) 441-1091


  • Kershaw, Lexington, Newberry, Richland
    2000 Hampton Street
    Columbia, SC 29204
    Phone: (803) 576-2749
    Fax: (803) 576-2993
    Nights / Weekends:
    (888) 554-9915
  • Chester, Fairfield, Lancaster, York
    P.O. Box 817
    1833 Pageland Highway
    Lancaster, SC 29720
    Phone: (803) 286-9948
    Fax: (803) 286-5418
    Nights / Weekends:
    (888) 554-9915
  • Aiken, Barnwell, Edgefield, Saluda
    222 Beaufort Street, NE
    Aiken, SC 29801
    Phone: (803) 642-1618
    Fax: (803) 643-8386
    Nights / Weekends:
    (888) 554-9915

Pee Dee

  • Chesterfield, Darlington, Dillon, Florence, Marlboro, Marion
    145 E. Cheves Street
    Florence, SC 29506
    Phone: (843) 661-4830
    Fax: (843) 661-4859
    Nights / Weekends:
    (843) 915-8845
  • Clarendon, Lee, Sumter
    P.O. Box 1628
    105 North Magnolia Street
    Sumter, SC 29150
    Phone: (803) 773-5511
    Fax: (803) 775-9941
    (843) 915-8845
  • Georgetown, Horry, Williamsburg
    1931 Industrial Park Road
    Conway, SC 29526-5482
    Phone: (843) 915-8804
    Fax: (843) 365-0085
    (843) 915-8845


  • Anderson, Oconee
    220 McGee Road
    Anderson, SC 29625
    Phone: (864) 260-5801
    Fax: (864) 260-5623
    Nights / Weekends:
    (866) 298-4442
  • Abbeville, Greenwood, Laurens, McCormick
    1736 S. Main Street
    Greenwood, SC 29646
    Phone: (864) 227-5947
    Fax: (864) 942-3690
    Nights / Weekends:
    (866) 298-4442
  • Cherokee, Greenville, Pickens, Spartanburg, Union
    P.O. Box 2507
    200 University Ridge
    Greenville, SC 29602-2507
    Phone: (864) 372-3133
    Fax: (864) 282-4373
    Nights / Weekends:
    (866) 298-4442

DHEC Bureau of Disease Control, Division of Acute Disease Epidemiology

1751 Calhoun Street, Box 101106
Columbia, SC  29211
Phone: (803) 898-0861
Fax: (803) 898-0897
Nights / Weekends: 1-888-847-0902