Pickens Regional Offices

For questions concerning Air, Land, Water, Septic Tanks, Food Permits, and Rabies, or to submit private well samples , please contact:

Main Office:

Upstate EA Greenville
200 University Ridge
Greenville, SC 29601
(864) 372-3273 (office)
(864) 282-4371 (fax)

To submit septic tank applications , please visit:

Pickens One Stop Shop
Pickens County Permit Office
222 McDaniel Ave
Room B-10
Pickens, SC 29671
(864) 898-5950

To report chemical spills, oil spills, or fish kills, call our
toll-free 24-hour emergency response line at 1-888-481-0125


DHEC Locations Businesses General Public Professionals